| Episode # |
Original Air Date |
Guests |
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| Season 1
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| 1. | 1-1 | 06 Jul 01 | Joey Lauren Adams, Peter Berg, Kevin James, and Jeanne Tripplehorn
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| 2. | 1-2 | 22 Nov 01 | Vince Vaughn, Garry Shandling, Cheri Oteri, and Peter Falk
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| 3. | 1-3 | 22 Apr 02 | Christian Slater, Illeana Douglas, Jeff Goldblum, and Fred Willard
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| 4. | 1-4 | 29 Apr 02 | Ron Livingston, Kevin Pollack, Sarah Silverman, and Rod Steiger
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| 5. | 1-5 | 06 May 02 | Andy Dick, Daryl Hannah, and Marilyn Manson
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| 6. | 1-6 | 13 May 02 | Sean Astin, Bonnie Hunt, Kevin James, and Ray Romano
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| 7. | 1-7 | 27 May 02 | Saffron Burrows, Faizon Love, Michael Rapaport, and Sarah Silverman
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| 8. | 1-8 | 03 Jun 02 | Jennifer Beals, Adam Goldberg, Seth Green, and Dwight Yoakum
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| 9. | 1-9 | 30 Sep 02 | David Cross, Famke Janssen, Denis Leary, and Martha Plimpton
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| 10. | 1-10 | 07 Oct 02 | Sean Combs, John Leguizamo, Juliette Lewis, and Vincent Pastore
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| Season 2
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| 11. | 2-1 | 20 Jan 03 | Ben Affleck, Colin Farrell, Jennifer Garner, and Kevin Smith
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| 12. | 2-2 | 27 Jan 03 | Dom Deluise, Peter Falk, John Herzfeld, and Richard Lewis
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| 13. | 2-3 | 03 Feb 03 | Peter Bogdanovich, Larry Miller, Penelope Ann Miller, and Liev Schreiber
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| 14. | 2-4 | 10 Feb 03 | Ed Asner, Ed Begley, Jr., Carrie Fisher, and Blair Underwood
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| 15. | 2-5 | 17 Feb 03 | David Byrne, Dave Eggers, Janeane Garofalo, and Joe Pantoliano
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| 16. | 2-6 | 24 Feb 03 | Louis C.K., Illeana Douglas, Will Ferrell, and Eddie Izzard
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| 17. | 2-7 | 03 Mar 03 | Vince Vaughn, Cole Hauser, Rory Cochrane, and Brian Cox
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| 18. | 2-8 | 22 Sep 03 | John Landis, David Alan Grier, Leland Orser, and Fran Drescher
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| 19. | 2-9 | 29 Sep 03 | Beverly D'Angelo, Rosie Perez, Cathy Moriarty, and Catherine Kellner
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| 20. | 2-10 | 06 Oct 03 | James Caan, Will Ferrell, Mary Steenburgen, and Zooey Deschanel
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| 21. | 2-11 | 13 Oct 03 | Sean Hayes, Katie Holmes, Patricia Clarkson, and Oliver Platt
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| 22. | 2-12 | 20 Oct 03 | Peter Berg, Judd Apatow, Famke Janssen, and Paul Rudd
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| 23. | 2-13 | 27 Oct 03 | Lili Taylor, Maggie Gyllenhaal, John Sayles, and Vanessa Martinez
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| Season 3
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| 24. | 3-1 | 09 Apr 04 | Gina Gershon, Dennis Farina, Ron Livingston, and Faizon Love
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| 25. | 3-2 | 16 Apr 04 | Kevin James, Tony Shalhoub, Richard Lewis, and Burt Reynolds
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| 26. | 3-3 | 23 Apr 04 | Kevin Smith, George Carlin, Jason Biggs, and Stephen Root
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| 27. | 3-4 | 30 Apr 04 | Joe Mantegna, Bob Odenkirk, Michael McKean, and Jeff Garlin
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| 28. | 3-5 | 07 May 04 | Jeff Ross, Hector Elizando, Kevin Pollak, and Laura Kightlinger
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| 29. | 3-6 | 14 May 04 | Laura Dern, Ted Danson, Mary Steenburgen, and Ernie Hudson
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| 30. | 3-7 | 21 May 04 | Jennifer Esposito, Barry Pepper, Luis Guzman, and Stephen Dorff
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| 31. | 3-8 | 28 May 04 | Alec Baldwin, Peter Dinklage, Carrie Fisher, and Tracey Ullman
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| 32. | 3-9 | 04 Jun 04 | Dom DeLuise, Burt Reynolds, Charles Durning, and Charles Nelson Reilly
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| 33. | 3-10 | 11 Jun 04 | John Waters, Colin Quinn, Danny Aiello, and Delroy Lindo
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| 34. | 3-11 | 18 Jun 04 | Isaac Mizrahi, Alan Cumming, Faizon Love, and Amy Irving
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| 35. | 3-12 | 25 Jun 04 | David Cross, Molly Shannon, George Hickenlooper, and Phillip Baker Hall
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| 36. | 3-13 | 02 Jul 04 | Michael Madsen, Richard Donner, Ray Romano, and Ron Eldard
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| 37. | 3-14 | 10 Sep 04 | Neve Campbell, Henry Winkler, Dave Foley, and Jeff Garlin
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| 38. | 3-15 | 08 Oct 04 | Peter Berg, Billy Bob Thornton, Brian Grazer, and H.G (Buzz) Bissinger
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| 39. | 3-16 | 10 Dec 04 | Martin Scorsese
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| Season 4
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| 40. | 4-1 | 01 Apr 05 | David Milch, Tim Olyphant, Michael Rapaport, and Jay Mohr
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| 41. | 4-2 | 08 Apr 05 | Tracy Morgan, Jeffrey Tambor, Bonnie Hunt, and Jason Bateman
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| 42. | 4-3 | 15 Apr 05 | Rob Zombie, Bruce Campbell, Roger Corman, and Faizon Love
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| 43. | 4-4 | 22 Apr 05 | Michael De Luca, Luis Guzman, Michael Chiklis, and Henry Rollins
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| 44. | 4-5 | 29 Apr 05 | David Duchovny, Dax Shepard, Tim Blake Nelson, and Stephen Root
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| 45. | 4-6 | 06 May 05 | Bill Maher, Alanis Morissette, Rosanna Arquette, and Bob Odenkirk
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| 46. | 4-7 | 20 May 05 | Frank Darabont, Alan Cumming, Harry Shearer, and Fred Willard
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| 47. | 4-8 | 02 Jun 05 | Tony Hawk, Stacy Peralta, Seth MacFarlane, and Jon Heder
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| 48. | 4-9 | 17 Jun 05 | Kevin Smith, Jason Lee, Stan Lee, Mark Hamill, and J.J. Abrams
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| 49. | 4-10 | 24 Jun 05 | Adam Goldberg, Christina Ricci, Giovanni Ribisi, and Steven Drozd
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| Season 5
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| 50. | 5-1 | 01 Feb 08 | Peter Billingsley, Justin Long, Keir O'Donnell, and Vince Vaughn
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